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NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance and a 12-kD gamma subunit

SKU: 7567306061

4.1
PLN123.75 PLN143.75

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NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance and a 12-kD gamma subunitThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain

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Description

and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al

and this interaction may play a role in ovulation and fertilization

Multiple processed pseudogenes derived from this gene are present in the genome

L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues

NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance and a 12-kD gamma subunitThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain

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