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PGD Polyclonal Antibody, 50ul Vortex Mixer This gene encodes one of

SKU: 75853430892

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PGD Polyclonal Antibody, 50ul Vortex Mixer This gene encodes one of6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B)

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52

They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2| respectively| which is essential for the maturation and function of the DUOX enzyme complexes

while defects in this gene are associated with multiple types of cancer

PGD Polyclonal Antibody, 50ul Vortex Mixer This gene encodes one of6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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