PXR Polyclonal Antibody, 100ul General Lab Use MAPKAPK3 encodes a member of

MAPKAPK3 encodes a member of the Ser/Thr protein kinase family (mitogen-activated protein kinase-activated protein kinase 3)

|PTM:Phosphorylation has no effect on Catalytic activity

implying different ligand specificity

The encoded protein (caspase 2) may function in stress-induced cell death pathways

PXR Polyclonal Antibody, 100ul General Lab Use MAPKAPK3 encodes a member ofThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including