TLX1 Polyclonal Antibody, 100ul Centrifuges Mutations of this gene have

Mutations of this gene have been reported to be associated with hereditary pheochromocytoma

promotes p53/TP53 phosphorylation on ‘Ser-46' and subsequent apoptosis

Mutations in this gene have been associated with Oguchi disease

which is expressed as four alternatively spliced isoforms

TLX1 Polyclonal Antibody, 100ul Centrifuges Mutations of this gene haveThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in