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Rpb1 CTD(Phospho-Ser2) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Mutations in this gene lead

SKU: 76619174717

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Rpb1 CTD(Phospho-Ser2) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Mutations in this gene leadThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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Description

Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia

A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling

The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation

Belongs to the CREG family

Rpb1 CTD(Phospho-Ser2) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Mutations in this gene leadThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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