HMCS1 Polyclonal Antibody, 100ul Human Genome Knockout Libraries Alternative splicing of this gene

Alternative splicing of this gene results in four transcript variants encoding different isoforms

Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene

Himmelfarb et al

Diseases associated with PINX1 include hepatocellular carcinoma

HMCS1 Polyclonal Antibody, 100ul Human Genome Knockout Libraries Alternative splicing of this geneCatalytic activity: Acetyl CoA + H(2)O + acetoacetyl CoA = (S) 3 hydroxy 3 methylglutaryl CoA + CoA.,This enzyme condenses acetyl CoA with acetoacetyl CoA to form HMG CoA, which is the substrate for HMG CoA reductase.,pathway: Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R) mevalonic acid from acetyl CoA: step 2 3.,Belongs to the HMG CoA synthase family.,