PLXB1 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants of this gene have been reported

have been identified but their biological validity has not been established

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|Contains 2 cystatin domains

PLXB1 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Multiple alternatively spliced transcript variantsdisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: