PDC6I Polyclonal Antibody, 20ul Insect Expression VAV3 is a member of

VAV3 is a member of the VAV gene family

Belongs to the eukaryotic RPA43 RNA polymerase subunit family

The protein encoded by this gene contains a RING-H2 finger motif

The subcellular localization and function of this protein are modulated by post-translational modifications

PDC6I Polyclonal Antibody, 20ul Insect Expression VAV3 is a member ofThis gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium dependent manner. This gene product also binds to