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MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences the encoded protein lacks caspase

SKU: 78347081649

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MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences the encoded protein lacks caspaseMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8

The microtubule-associated proteins can be divided into two groups

effectively minimizing sample loss

The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation

MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences the encoded protein lacks caspaseMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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