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Presenilin 2(Phospho Ser330) Polyclonal Antibody, 100ul Protein Post-translational Modification Two alternatively spliced transcript variants

SKU: 78772627467

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SEK123.75 SEK170.75

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Presenilin 2(Phospho Ser330) Polyclonal Antibody, 100ul Protein Post-translational Modification Two alternatively spliced transcript variantsAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,

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Description

Two alternatively spliced transcript variants have been described for this gene

Belongs to the fibroblast growth factor-binding protein family

bone resorption

it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Presenilin 2(Phospho Ser330) Polyclonal Antibody, 100ul Protein Post-translational Modification Two alternatively spliced transcript variantsAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,

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