HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies Defects in this gene are

Defects in this gene are a cause of Pitt-Hopkins syndrome

It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis

Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins

They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens

HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies Defects in this gene areHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear