ENX-2 Polyclonal Antibody, 50ul CellSafe™ Mutations in BTK cause X-linked

Mutations in BTK cause X-linked agammaglobulinemia type 1

prefoldin like chaperone) encodes member of the prefoldin family of molecular chaperones

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules

ENX-2 Polyclonal Antibody, 50ul CellSafe™ Mutations in BTK cause X-linkedEZH1 is a component of a noncanonical Polycomb repressive complex 2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).