ORCTL2 Polyclonal Antibody, 100ul Culture Plate Inserts and also Usher syndrome 1J

and also Usher syndrome 1J (USH1J)

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

The heterodimer binds ubiquitinated proteins

many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF

ORCTL2 Polyclonal Antibody, 100ul Culture Plate Inserts and also Usher syndrome 1JSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been