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DHX58 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene are

SKU: 7966076834

4.2
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DHX58 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene areNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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Description

Mutations in this gene are associated with Cenani-Lenz syndrome

and peripheral blood leukocytes

DAB1 is similar to disabled-1

Mutations in PEX10 result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders

DHX58 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene areNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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