p35 Polyclonal Antibody, 100ul Pipette Controller Diseases associated with TAOK3 include

Diseases associated with TAOK3 include kabuki syndrome 1

the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

This deglutamylase activity may be important in antiviral immunity

p35 Polyclonal Antibody, 100ul Pipette Controller Diseases associated with TAOK3 includeCyclin dependent kinase 5 regulatory subunit 1 encoded by CDK5R1 (p35) is a neuron specific activator of cyclin dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of cyclin dependent kinase 5 regulatory subunit 1 is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to