LMTK1 Polyclonal Antibody, 20ul Cell Culture Dishes Suppressor of cytokine signaling 2

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

Several transcript variants encoding different isoforms have been described for this gene

Interacts with pre-ribosome complex

This protein is found associated with endosomal membranes

LMTK1 Polyclonal Antibody, 20ul Cell Culture Dishes Suppressor of cytokine signaling 2The protein encoded by this gene contains a tyrosine kinase domain at the N terminus and a proline rich domain at the C terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre requisite for the induction of growth arrest and or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms