EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers multiple familial trichoepithelioma

multiple familial trichoepithelioma

This gene is a member of the Gal/GalNAc/GlcNAc (galactose/N-acetylgalactosamine/N-acetylglucosamine) 6-O-sulfotransferase (GST) family

The mRNA of this gene is subject to multiple RNA editing events

which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers multiple familial trichoepitheliomaThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.