DSE Rabbit Polyclonal Antibody, 100ul Centrifuges Expression of this protein is

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

down-regulated by phorbol 12-myristate 13-acetate

Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease

This gene has multiple transcript variants which are predicted to encode distinct isoforms

DSE Rabbit Polyclonal Antibody, 100ul Centrifuges Expression of this protein isThe protein encoded by this gene is a tumor rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D glucuronic acid to L iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA A24 restricted and tumor specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural