SPTN2 Rabbit Polyclonal Antibody, 100ul Live Cell Imaging The gene is a tumor

The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade

tissue specificity:Expressed in brain at low level

PSAP (prosaposin) encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A

The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis

SPTN2 Rabbit Polyclonal Antibody, 100ul Live Cell Imaging The gene is a tumorSpectrins are principle components of a cell's membrane cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2) is called spectrin beta non erythrocytic 2 or beta III spectrin. It is related to but distinct from the beta II spectrin gene which is also known as spectrin beta non erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter