NEB2 Polyclonal Antibody, 20ul Cellular Function Assays VANGL1 encodes a member of

VANGL1 encodes a member of the tretraspanin family

which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons

Identification of the deletion

This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine

NEB2 Polyclonal Antibody, 20ul Cellular Function Assays VANGL1 encodes a member ofThis gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors.