IRS-1(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies A single nucleotide variant in

A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance

The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates

Mutations in this gene have been associated with Aicardi-Goutieres syndrome

The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases

IRS-1(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies A single nucleotide variant inThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.