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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments May function in transmigration of

SKU: 82028813953

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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments May function in transmigration ofThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

May function in transmigration of leukocytes through epithelial and endothelial tissues

subunit:Interacts with MKL1 and SRF

and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains

Nibrin is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins

Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments May function in transmigration ofThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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