SIP1 Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene have

Mutations in this gene have been associated with congenital insensitivity to pain

Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens

The C-C motif chemokine receptor 4 encoded by CCR4 belongs to the G-protein-coupled receptor family

Granzyme H is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells

SIP1 Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene haveZinc finger E box binding homeobox 2 encoded by ZEB2 is a member of the Zfh1 family of 2 handed zinc finger homeodomain proteins. It is located in the nucleus and functions as a DNA binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease Mowat Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.