ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements The cyclin dependent kinase inhibitor

The cyclin dependent kinase inhibitor 2D encoded by CDKN2D is a member of the INK4 family of cyclin-dependent kinase inhibitors

Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III

which encodes a structurally unrelated protein - Alex

This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers

ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements The cyclin dependent kinase inhibitorThis gene encodes a protein with several transmembrane domains a Rab11 binding domain and a lipid binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia however the pathogenicity of the mutation which may simply represent a polymorphism is unclear.