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Histone H4 (Acetyl Lys8) Polyclonal Antibody, 100ul Bio-Reaction Tube This gene is encodes a

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Histone H4 (Acetyl Lys8) Polyclonal Antibody, 100ul Bio-Reaction Tube This gene is encodes aHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme

H3 Lys-9 trimethylation is also required to direct DNA methylation at pericentric repeats

This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2| which appears to be a duplication of the A1 locus

Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance

Histone H4 (Acetyl Lys8) Polyclonal Antibody, 100ul Bio-Reaction Tube This gene is encodes aHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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