EpoR(Phospho Tyr426) Polyclonal Antibody, 100ul Cell Culture Flasks Alternate splicing of EPN2 results

Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms

Members of the WIPI subfamily of WD40 repeat proteins

whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission

EpoR(Phospho Tyr426) Polyclonal Antibody, 100ul Cell Culture Flasks Alternate splicing of EPN2 resultsThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce