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TAF1B Polyclonal Antibody, 50ul Culture Plate Inserts Mutations in this gene and/or

SKU: 8382011274

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TAF1B Polyclonal Antibody, 50ul Culture Plate Inserts Mutations in this gene and/orInitiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA binding protein (TBP) and three TBP associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1 specific TAFs. Multiple transcript variants encoding different

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Description

Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia

and activating several members of the Ras family of GTPases

This gene encodes a member of the membrane-spanning 4A gene family| members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues

a minimal activity on neutrophils

TAF1B Polyclonal Antibody, 50ul Culture Plate Inserts Mutations in this gene and/orInitiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA binding protein (TBP) and three TBP associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1 specific TAFs. Multiple transcript variants encoding different

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