DNJB6 Polyclonal Antibody, 20ul Protein Research Mutations at this locus have

Mutations at this locus have been associated with Rett syndrome

Three transcript variants encoding different isoforms have been found for MOB1B

Defects in SNCA have been implicated in the pathogenesis of Parkinson disease

Alternative splicing of DYRK1A generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region

DNJB6 Polyclonal Antibody, 20ul Protein Research Mutations at this locus haveThis gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this