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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome The encoded protein is related

SKU: 84113758807

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome The encoded protein is relatedERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis

suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells

Expression of this gene may be downregulated in pancreatic cancer

ANXA10 encodes a member (annexin A10) of the annexin family

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome The encoded protein is relatedERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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