ANGP2 Polyclonal Antibody, 50ul Organelle Studies IRX3 is a member of

IRX3 is a member of the Iroquois homeobox gene family (see IRX1

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling

ANGP2 Polyclonal Antibody, 50ul Organelle Studies IRX3 is a member ofThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.