Actinin-Alpha3 Polyclonal Antibody, 50ul Stepper A chromosomal aberration involving PSIP1

A chromosomal aberration involving PSIP1 is associated with pediatric acute myeloid leukemia (AML) with intermediate characteristics between M2-M3 French-American-British (FAB) subtypes

induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis

and is concentrated at the leading edge of migratory cells

the arylsulfatase subfamily

Actinin-Alpha3 Polyclonal Antibody, 50ul Stepper A chromosomal aberration involving PSIP1ACTN3 encodes a member of the alpha actin binding protein gene family. Actinin alpha 3 (gene pseudogene) is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non coding variants; the reference genome represents the coding allele. The non functional allele of ACTN3