Phospho-BRCA2 (S3291) Polyclonal Antibody, 100ul Modified Oligos RAN-binding protein-17 is a member

RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors

The disease affects the brain and central nervous system

The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads

such as GTPBP5

Phospho-BRCA2 (S3291) Polyclonal Antibody, 100ul Modified Oligos RAN-binding protein-17 is a memberInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is