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Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Two modes of SLAM signaling

SKU: 84648534649

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Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Two modes of SLAM signalingRAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome.

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Description

Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates

subunit:Interacts with CSK/c-Src

Three alternatively spliced transcript variants that encode different protein isoforms have been described for RBBP5

It mediates adhesive interactions important for antigen-specific immune response

Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Two modes of SLAM signalingRAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome.

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