PRP8 Polyclonal Antibody, 20ul Virus Packaging Filamin-A encoded by FLNA is

Filamin-A encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins

The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin

It is a receptor for the CC chemokine - MIP-1

and tissue differentiation

PRP8 Polyclonal Antibody, 20ul Virus Packaging Filamin-A encoded by FLNA isPre mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2 and U12 dependent spliceosomes, and found to be essential for the catalytic step II in pre mRNA splicing process. It contains several WD repeats, which function in protein protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis