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Ku-80 Polyclonal Antibody, 100ul[BT-AP04901] Microbial Genome Editing Amplification and/or overexpression of this

SKU: 8478382237

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Ku-80 Polyclonal Antibody, 100ul[BT-AP04901] Microbial Genome Editing Amplification and/or overexpression of thisX ray repair cross complementing protein 5 encoded by XRCC5 is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events.

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Description

Amplification and/or overexpression of this gene has been reported in numerous cancers| including breast and ovarian tumors

SIRT3 encodes a member of the sirtuin family of proteins

GO annotations related to this gene include beta-amyloid binding

May also be involved in cardiac development

Ku-80 Polyclonal Antibody, 100ul[BT-AP04901] Microbial Genome Editing Amplification and/or overexpression of thisX ray repair cross complementing protein 5 encoded by XRCC5 is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events.

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