MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been reported

H3 Lys-9 trimethylation is also required to direct DNA methylation at pericentric repeats

Transcriptional activator

may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes

MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis Alternatively spliced transcript variants encodingThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and