SETBP Rabbit Polyclonal Antibody, 20ul Immunology alternative products:At least 4 isoforms|

alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

which is characterized by skeletal dysplasia with generalized limb bone shortening

It has been shown to play a central role in the physiological regulation of programmed cell death

SETBP Rabbit Polyclonal Antibody, 20ul Immunology alternative products:At least 4 isoforms|This gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.