PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection The type II keratins are

The type II keratins are clustered in a region of chromosome 12q13

Overexpression of PMEPA1 may play a role in multiple types of cancer

The unphosphorylated form is not subject to ubiquitination

Diseases associated with SUPT3H include blastic plasmacytoid dendritic cell

PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection The type II keratins arePEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.