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Ref-1 Polyclonal Antibody, 20ul[BT-AP07734] Glassware Sets This protein has been shown

SKU: 86623706754

4.2
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Ref-1 Polyclonal Antibody, 20ul[BT-AP07734] Glassware Sets This protein has been shownApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

This protein has been shown to form a stable heterodimer with the family member RAD51C

SLC16A2 is subject to X-chromosome inactivation

a positive regulator of programmed cell death

alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains

Ref-1 Polyclonal Antibody, 20ul[BT-AP07734] Glassware Sets This protein has been shownApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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