ATF-6Beta Polyclonal Antibody, 100ul Cell Screening and Imaging resulting in five different isoforms

resulting in five different isoforms with distinct properties

which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis

This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4|5-bisphosphate to 1D-myo-inositol 1|4|5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor

ATF-6Beta Polyclonal Antibody, 100ul Cell Screening and Imaging resulting in five different isoformsThe protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6 alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER