p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix ring-box 1 (Rbx1) and Cullin2

ring-box 1 (Rbx1) and Cullin2 (Cul2)

and epsilon subunits

Transcription repressor ZNF278/PATZ is found to interact with this protein| and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix ring-box 1 (Rbx1) and Cullin2TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni