GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates recognizing nonreducing terminal sugars and

recognizing nonreducing terminal sugars and their anomeric linkages

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

is associated with the chromosome 9 gene encoding endoglin protein

This gene encodes a protein that contains a DNA-binding domain

GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates recognizing nonreducing terminal sugars andThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.