c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis presenilin-2

presenilin-2

Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70

such as ARSK

This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II

c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis presenilin-2This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a