HDAC5(Phospho Ser498) Polyclonal Antibody, 50ul Palm Micro Centrifuges Polymorphisms in this gene have

Polymorphisms in this gene have also been associated with asthma susceptibility

A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein

The genome has two identical copies of this gene within a palindromic region

The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains| three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

HDAC5(Phospho Ser498) Polyclonal Antibody, 50ul Palm Micro Centrifuges Polymorphisms in this gene haveHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3