ERCC2 Polyclonal Antibody, 20ul PCR Series have been reported in a

have been reported in a variety of solid tumors

but not IL2

Amplification and/or overexpression of this gene has been reported in numerous cancers| including breast and ovarian tumors

The encoded proteins binds to its own promoter as well as to that of several target genes

ERCC2 Polyclonal Antibody, 20ul PCR Series have been reported in aThe nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2 TFIIH complex. The gene product has ATP dependent DNA helicase activity and belongs to the RAD3 XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer prone syndrome