Flt3(Phospho Tyr599) Polyclonal Antibody, 100ul Cell Culture Flasks Mediator complex subunit 23 encoded

Mediator complex subunit 23 encoded by MED23 is a subunit of the CRSP (cofactor required for SP1 activation) complex

a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity

The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor

Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4

Flt3(Phospho Tyr599) Polyclonal Antibody, 100ul Cell Culture Flasks Mediator complex subunit 23 encodedThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,