RM43 Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) tissue specificity:Expressed in lung

tissue specificity:Expressed in lung

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

thereby allowing control of cellular proliferation and differentiation

Mutations in this gene are implicated in Bardet-Biedl syndrome

RM43 Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) tissue specificity:Expressed in lungMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S