I5P2 Rabbit Polyclonal Antibody, 100ul Lysosome MSH2 is frequently mutated in

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

apocrine gland

Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response

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I5P2 Rabbit Polyclonal Antibody, 100ul Lysosome MSH2 is frequently mutated inThis gene encodes a member of a family of inositol polyphosphate 5 phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria and associates with membranes through an isoprenyl modification near the C terminus. Alternatively spliced transcript variants of this gene have been described.