DHB1 Polyclonal Antibody, 20ul Cell Culture Flasks Aberrant expression of this gene

Aberrant expression of this gene may promote tumorigenesis

The protein encoded by this gene belongs to the leucine-rich repeat superfamily

Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

DHB1 Polyclonal Antibody, 20ul Cell Culture Flasks Aberrant expression of this geneThis gene encodes a member of the 17beta hydroxysteroid dehydrogenase family of short chain dehydrogenases reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4 androstenedione,