CIR1A Rabbit Polyclonal Antibody, 50ul Vortex Mixer Homozygous mutations of this gene

Homozygous mutations of this gene were observed in primary lymphoma and colon cancer

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

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This cytokine is expressed in B cell lineage cells

CIR1A Rabbit Polyclonal Antibody, 50ul Vortex Mixer Homozygous mutations of this geneThis gene encodes a WD40 repeat containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.